Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. Instead, youll start by receiving just one treatment course of Injectafer. <> The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Consult your pharmacist or local waste disposal company. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. They can tell you about other medications that may work well for you. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Brand-name medications usually cost more than generics. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Drug interactions may change how your medications work or increase your risk for serious side effects. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Injectafer is approved to treat iron deficiency anemia (IDA). These people may lose weight as their anemia improves because theyre more active. But keep in mind that in this study, delayed allergic reaction only occurred in one person. It's a more immediate treatment than supplements or dietary changes. If you have questions about side effects, call your doctor. Side effects are uncomfortable reactions to medications or drugs. Find out what health conditions may be a health risk when taken with Venofer Vial And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Injectafer isnt a medication that youll take regularly on a schedule. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. It can also cause skin irritation and redness. An LSD comedown is when the mental and hallucinatory effects have worn . Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Together, you and your doctor can develop a treatment plan thats best for you. This survey is being conducted by the WebMD marketing sciences department. If youre interested in finding an alternative to Injectafer, talk with your doctor. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Use of the term female in this article refers to sex assigned at birth. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Call your doctor for medical advice about side effects. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Iron infusions are given directly into a vein. The iron released by this drug does pass into human breast milk. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. But some people have a delayed allergic reaction to certain drugs. VenAccess is a trademark of Vifor (International) Inc. Switzerland. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. weakness. But if they become more severe or dont go away, talk with your doctor or pharmacist. However, side effects at the 150 mg dose may indicate that you might not . Those going through thismedical conditionshould speak to theircare teamfor support andguidance. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. taste impairment. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing * This is a partial list of mild side effects from Injectafer. 5 0 obj For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Dizziness. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. <> And this could lead to weight gain, if they increase their food intake. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Here we look at how Injectafer and Venofer are alike and different. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. I had Venofer infusions, 2 rounds now in the span of three years. Effectiveness of Injectafer compared with iron thats taken by mouth. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. This includes your doctors, nurses, pharmacists, and dentists. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Some products that may interact with this drug include: vitamin products, other iron-containing products. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. All rights reserved. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Heart failure: Could a low sodium diet sometimes do more harm than good? Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. Allergic reactions typically occur the first time your body is exposed to a drug. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. There are currently no generic forms of either drug. Some drugs may have another patient information leaflet. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Any long-term side effects/dangers from iron infusions? Call your doctor for instructions if you miss an appointment for your Venofer injection. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. You may need extra iron because of blood loss during kidney dialysis. generalized weakness. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. (A medication class describes a group of drugs that work in the same way.). Theseside effectscan range from being mild tosevere. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Venofer is for use in adults and children at least 2 years old. <> This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Hemoglobin is a protein thats found in your RBCs. Is the ketogenic diet right for autoimmune conditions? The Injectafer dosage your doctor prescribes will depend on your body weight. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. This website is intended for use by US patients. Before taking Injectafer, talk with your doctor about your health history. Yes, in some cases it may. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Its given by either intravenous (IV) infusion or slow IV injection. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. But for other people, their IDA returns after treatment with Injectafer. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Pain in your limbs. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Can poor sleep impact your weight loss goals? Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Most people will metabolize medication by half every time it circulates the body. You will be watched closely by your doctor for 30 minutes after each dose. This product may contain inactive ingredients, which can cause allergic reactions or other problems. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Phosphorus is an electrolyte that your body needs in order to make energy. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. As with all medications, the cost of Injectafer can vary. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). I hope you found answers and are feeling better now. Venofer is not for treating other forms of anemia not caused by iron deficiency. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. <> Properly discard this product when it is expired or no longer needed. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. This medicine may cause serious types . 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Once inside your body, ferric carboxymaltose releases iron into your system. We cancelled my 5th because of the reaction. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Renal elimination is negligible. Terminal half-life ranges from 7 to 12 hours. If you notice other effects not listed above, contact your doctor or pharmacist. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. These lists dont include all possible side effects. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Side effectswill last a very long time if the cause of them is not resolved. Low blood pressure. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Someside effectsare temporary or last as long as the person continues takingprescription medicine. We comply with the HONcode standard for trustworthy health information. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. With anemia, you have a low level of red blood cells (RBCs) in your body. This medication is given by injection into a vein as directed by your doctor. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. But you likely wont feel the drug working inside of you. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. There may be drug take-back programs in your area. Fortunately, knowing how longside effectslast can help those suffering know what to donext. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Otherwise, call a poison control center right away. People from different ethnic backgrounds process medications differently. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Learn about uses, cost, how it works, and more. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. With IDA, you have low hemoglobin levels. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. If needed, theyll recommend treatment, including certain medications. Throw away unused or expired drugs. 1 0 obj Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Here we look at how Injectafer and Feraheme are alike and different. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. With IDA, you have low hemoglobin levels. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Venofer Side Effects. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Health careproviderscan provide information on how longside effectslast by checking amedication guide. stream If your symptoms or health problems do not get better or if they become worse, call your doctor. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. With this condition, you also have a low hemoglobin level. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Injectafer is a brand-name prescription drug. However, be sure to take the dosage your doctor prescribes for you. Feraheme also comes as a liquid thats given by IV infusion. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Its responsible for carrying oxygen throughout your body. Data on file, American Regent, Inc. 1. What is Venofer? endobj Things to remember when you fill your prescription. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Blood tests may be needed to check for unwanted effects. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. And this can lead to anemia, including IDA. Why is the range so wide? The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. You may report side effects to the FDA at 1-800-332-1088. These changes could help improve your anemia on a long-term basis. What is the latest research on the form of cancer Jimmy Carter has? And this can affect how well those parts of your body are able to work. You can also write a reminder on your calendar. Venofer treatment may be repeated if iron deficiency reoccurs. And this person had gotten their first dose of the drug without having an allergic reaction. Call your doctor right away if you have serious side effects. Mental healthdisorders like depression may requireantidepressantsto treat. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Examples of these side effects include dizziness and nausea. How is Venofer (iron sucrose) given? There are different types of anemia, but IDA is the most common type. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Youll receive doses of either drug by a healthcare professional at a medical facility. The study also didnt show if one treatment was worse than the other. This is not a complete list of side effects and others may occur. As a result, you may not make as much EPO as usual. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Tell all of your health care providers that you take Venofer. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. You may report side effects to the FDA at 1-800-332-1088. Many people using this medication do not have serious side effects. Pain, swelling, or redness at the injection site may occur. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Change in taste. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Possibleside effectsareweight gainand suicidal thoughts. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Generics tend to cost less than brand-name drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Joint pain. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. It belongs to a class of medications called iron replacement products. No, you most likely wont take Injectafer long term. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. The drug helps increase your hemoglobin level back to a value thats within the normal range. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. However, many people have no side effects or only have minor side effects. All of the people took iron by mouth for 2 weeks. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. <> Understanding what thoseside effectsare can lead to a strategy to prevent them. These are not all of the side effects that may occur. In the second group, some people switched from taking iron by mouth to taking Injectafer. Patients with celiac disease (gluten intolerance). While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. (IV iron is absorbed by the body more rapidly than oral iron.) % US residents can call their local poison control center at 1-800-222-1222. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. There isnt a known interaction between Injectafer and alcohol. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. reactions at the site of the injection. With IV infusion, the drug is given as a slow drip into your vein over a period of time. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs.